Analysis of the structure of acute poisoning with modern psychoactive substances

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Abstract

Introduction. The article presents the epidemiological analysis of the structure of acute poisonings with modern psychoactive substances.

The aim of the study was to analyze the structure of acute poisonings with modern psychoactive substances among patients hospitalized in General hospitals for 2019 to improve preventive measures.

Material and methods. There were used data obtained from the consolidated accounting documents of branches of the Centre for the treatment of acute poisoning. The aggregation of the material used numerical characteristics of the variables with the assessment of their accuracy and reliability, the significance of differences increased non-parametric Pearson criterion.

Results. The prevalence in biological fluids in hospitalized patients of γ-hydroxybutyrate was 46.6% (1452), synthetic α-PVP - 20,2% (631), synthetic opioids (methadone) and 13.2% (413). In the overall structure of acute poisonings registered in 2019, the proportion of poisoning with modern drugs amounted to 22.2% (4442), the case-fatality rate is 0.3%, which proves its high epidemiological significance. In the course of studying the dynamic characteristics of the epidemiological process the main peaks of the detection of psychoactive substances among the total number of performed laboratory research were established to be noted in July (52%), August (60,8%) and November (54,3%) 2019 based on the analysis conclusions are made about the feasibility of improving the system of prevention of acute poisonings with modern psychoactive substances at the pre-hospital and hospital stages.

About the authors

A. G. Sinenchenko

I.I. Dzhanelidze Research Institute of Emergency Medicine

Author for correspondence.
Email: andreysin2013@yandex.ru
ORCID iD: 0000-0003-2815-3108

PhD, head of the department of emergency psychiatry, narcology and psycho-rehabilitation, the St. Petersburg I.I. Dzhanelidze Research Institute of Emergency Medicine.

e-mail: andreysin2013@yandex.ru

Russian Federation

A. H. Lodyagin

I.I. Dzhanelidze Research Institute of Emergency Medicine; I.I. Mechnikov North-Western State Medical University

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8672-2906
Russian Federation

M. M. Shilov

I.I. Mechnikov North-Western State Medical University; North-West Public Health Research Center

Email: noemail@neicon.ru
ORCID iD: 0000-0003-3256-2609
Russian Federation

B. V. Batotsyrenov

I.I. Dzhanelidze Research Institute of Emergency Medicine

Email: noemail@neicon.ru
ORCID iD: 0000-0003-4954-8977
Russian Federation

O. L. Balabanova

I.I. Dzhanelidze Research Institute of Emergency Medicine

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8636-9858
Russian Federation

I. A. Shikalova

I.I. Dzhanelidze Research Institute of Emergency Medicine

Email: noemail@neicon.ru
ORCID iD: 0000-0002-8209-2652
Russian Federation

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Copyright (c) 2024 Sinenchenko A.G., Lodyagin A.H., Shilov M.M., Batotsyrenov B.V., Balabanova O.L., Shikalova I.A.


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