Cracking the Code of Lumpy Skin Disease: Identifying Causes, Symptoms and Treatment Options for Livestock Farmers


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Abstract

The novel bovine viral infection known as lumpy skin disease is common in most African and Middle Eastern countries, with a significant likelihood of disease transfer to Asia and Europe. Recent rapid disease spread in formerly disease-free zones highlights the need of understanding disease limits and distribution mechanisms. Capripox virus, the causal agent, may also cause sheeppox and Goatpox. Even though the virus is expelled through several bodily fluids and excretions, the most common causes of infection include sperm and skin sores. Thus, vulnerable hosts are mostly infected mechanically by hematophagous arthropods such as biting flies, mosquitoes, and ticks. As a result, milk production lowers, abortions, permanent or temporary sterility, hide damage, and mortality occur, contributing to a massive financial loss for countries that raise cattle. These illnesses are economically significant because they affect international trade. The spread of Capripox viruses appears to be spreading because to a lack of effectual vaccinations and poverty in rural areas. Lumpy skin disease has reached historic levels; as a consequence, vaccination remains the only viable option to keep the illness from spreading in endemic as well as newly impacted areas. This study is intended to offer a full update on existing knowledge of the disease's pathological characteristics, mechanisms of spread, transmission, control measures, and available vaccinations.

About the authors

Devdhar Yadav

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

GSN Koteswara Rao

, Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management

Email: info@benthamscience.net

Deepika Paliwal

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Author for correspondence.
Email: info@benthamscience.net

Amit Singh

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

Aftab Alam

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

Pramod Kumar Sharma

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

Amareswarapu Surendra

K L College of Pharmacy, Koneru Lakshmaiah Education Foundation

Email: info@benthamscience.net

Prachi Varshney

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

Yogesh Kumar

Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University

Email: info@benthamscience.net

References

  1. Kiplagat SK, Kitala PM, Onono JO, Beard PM, Lyons NA. Risk factors for outbreaks of lumpy skin disease and the economic impact in cattle farms of Nakuru County, Kenya. Front Vet Sci 2020; 7: 259. doi: 10.3389/fvets.2020.00259 PMID: 32548130
  2. Tuppurainen ESM, Oura CAL. Review: lumpy skin disease: An emerging threat to Europe, the Middle East and Asia. Transbound Emerg Dis 2012; 59(1): 40-8. doi: 10.1111/j.1865-1682.2011.01242.x PMID: 21749675
  3. Lumpy Skin Disease. World Organisation for Animal Health 2021.
  4. Shen YJ, Shephard E, Douglass N, et al. A novel candidate HIV vaccine vector based on the replication deficient Capripoxvirus, Lumpy skin disease virus (LSDV). Virol J 2011; 8(1): 265. doi: 10.1186/1743-422X-8-265 PMID: 21624130
  5. Davies FG. Lumpy skin disease of cattle: A growing problem in Africa and the Near East. World Anim Rev 1991; 68(3): 37-42.
  6. El-Nahas EM, El-Habbaa AS, El-Bagoury GF, Radwan ME. Isolation and identification of lumpy skin disease virus from naturally infected buffaloes at Kaluobia, Egypt. Glob Vet 2011; 7(3): 234-7.
  7. Constable PD, Hinchcliff KW, Done SH, Grünberg W. Veterinary medicine: A textbook of the diseases of cattle, horses, sheep, pigs and goats. Elsevier Health Sciences 2016.
  8. Carn VM, Kitching RP. The clinical response of cattle experimentally infected with lumpy skin disease (Neethling) virus. Arch Virol 1995; 140(3): 503-13. doi: 10.1007/BF01718427 PMID: 7733823
  9. Jameel GH. Determination of complications decrease the risk factor in Cattle infected by lumpy skin disease virus in diyala province, Iraq. International Journal of Micro Biology. Genetics and Monocular Biology Research 2016; 2: 1-9.
  10. Tageldin MH, Wallace DB, Gerdes GH, et al. Lumpy skin disease of cattle: An emerging problem in the Sultanate of Oman. Trop Anim Health Prod 2014; 46(1): 241-6. doi: 10.1007/s11250-013-0483-3 PMID: 24097247
  11. Gumbe AA. Review on lumpy skin disease and its economic impacts in Ethiopia. J Dairy Vet Anim Res 2018; 7(2): 39-46.
  12. Empres-i. Available from: https://empres-i.apps.fao.org/epidemiology
  13. Choudhari AN, Moregaonkar SD, Gangane GR, Markandeya NM, Narladkar BW. Lumpy skin disease (lsd), an emerging disease in India: a review. Agric Rev 2020; 41(Of): 398-402. doi: 10.18805/ag.R-2018
  14. Sethi RK, Senapati SK, Selim AM, et al. Molecular epidemiology of lumpy skin disease outbreak in Odisha, India. Vet Res Commun 2022; 46(3): 711-7. doi: 10.1007/s11259-022-09886-8 PMID: 35459980
  15. Gari G, Waret-Szkuta A, Grosbois V, Jacquiet P, Roger F. Risk factors associated with observed clinical lumpy skin disease in Ethiopia. Epidemiol Infect 2010; 138(11): 1657-66. doi: 10.1017/S0950268810000506 PMID: 20233495
  16. Madi M, Mioulet V, King DP, Lomonossoff GP, Montague NP. Development of a non-infectious encapsidated positive control RNA for molecular assays to detect foot-and-mouth disease virus. J Virol Methods 2015; 220: 27-34. doi: 10.1016/j.jviromet.2015.04.002 PMID: 25864934
  17. Mulatu E, Feyisa A. Review: Lumpy skin disease. J Vet Sci Technol 2018; 9(535): 1-8.
  18. Coetzer JA, Tuppurainen E. Lumpy skin disease.In: Infectious diseases of livestock. 2004; 2: pp. 1268-76.
  19. Tasioudi KE, Antoniou SE, Iliadou P, et al. Emergence of lumpy skin disease in Greece, 2015. Transbound Emerg Dis 2016; 63(3): 260-5. doi: 10.1111/tbed.12497 PMID: 26991342
  20. Şevik M, Doğan M. Epidemiological and molecular studies on lumpy skin disease outbreaks in Turkey during 2014–2015. Transbound Emerg Dis 2017; 64(4): 1268-79. doi: 10.1111/tbed.12501 PMID: 27039847
  21. Tuppurainen ESM, Venter EH, Shisler JL, et al. Capripoxvirus diseases: Current status and opportunities for control. Transbound Emerg Dis 2017; 64(3): 729-45. doi: 10.1111/tbed.12444 PMID: 26564428
  22. Davies FG. Lumpy skin disease, an African capripox virus disease of cattle. Br Vet J 1991; 147(6): 489-503. doi: 10.1016/0007-1935(91)90019-J PMID: 1777792
  23. Burdin ML. The use of histopathological examinations of skin material for the diagnosis of lumpy skin disease in Kenya. Bull Epizoot Dis Afr 1959; 7: 27-36.
  24. Martin WB, Hay D, Crawford LV, Le Bouvier GL, Crawford EM. Characteristics of bovine mammillitis virus. J Gen Microbiol 1966; 45(2): 325-32. doi: 10.1099/00221287-45-2-325 PMID: 4291091
  25. Tuppurainen ES, Babiuk S, Klement E, Klement E. Epidemiology and Transmission. Lumpy Skin Disease 2018; pp. 53-62.
  26. Babiuk S, Bowden TR, Boyle DB, Wallace DB, Kitching RP. Capripoxviruses: An emerging worldwide threat to sheep, goats and cattle. Transbound Emerg Dis 2008; 55(7): 263-72. doi: 10.1111/j.1865-1682.2008.01043.x PMID: 18774991
  27. Al-Salihi K. Lumpy skin disease: Review of literature. In: Mirror of research in veterinary sciences and animals. 2014; 3: pp. (3)6-23.
  28. Ali H, Ali AA, Atta MS, Cepica A. Common, emerging, vector-borne and infrequent abortogenic virus infections of cattle. Transbound Emerg Dis 2012; 59(1): 11-25. doi: 10.1111/j.1865-1682.2011.01240.x PMID: 21733134
  29. Tuppurainen E, Alexandrov T, Beltrán-Alcrudo DJ. Lumpy skin disease-a manual for veterinarians. In: Food and Agriculture Organization of the United Nations. 2017.
  30. Khan YR, Ali A, Hussain K, et al. A review: Surveillance of lumpy skin disease (LSD) a growing problem in Asia. Microb Pathog 2021; 158: 105050. doi: 10.1016/j.micpath.2021.105050 PMID: 34146642
  31. Lubinga JC, Tuppurainen ESM, Stoltsz WH, Ebersohn K, Coetzer JAW, Venter EH. Detection of lumpy skin disease virus in saliva of ticks fed on lumpy skin disease virus-infected cattle. Exp Appl Acarol 2013; 61(1): 129-38. doi: 10.1007/s10493-013-9679-5 PMID: 23456606
  32. Lubinga JC, Tuppurainen ESM, Coetzer JAW, Stoltsz WH, Venter EH. Evidence of lumpy skin disease virus over-wintering by transstadial persistence in Amblyomma hebraeum and transovarial persistence in Rhipicephalus decoloratus ticks. Exp Appl Acarol 2014; 62(1): 77-90. doi: 10.1007/s10493-013-9721-7 PMID: 23975563
  33. Chihota CM, Rennie LF, Kitching RP, Mellor PS. Mechanical transmission of lumpy skin disease virus by Aedes aegypti (Diptera: Culicidae). Epidemiol Infect 2001; 126(2): 317-21. doi: 10.1017/S0950268801005179 PMID: 11349983
  34. Hanshaw JB, Plowright W, Weiss KE, Hanshaw JB. Cytomegaloviruses. Springer Berlin Heidelberg 1968.
  35. Panel EA. Scientific opinion on lumpy skin disease. EFSA J 2015; 13(1): 3986.
  36. Irons PC, Tuppurainen ESM, Venter EH. Excretion of lumpy skin disease virus in bull semen. Theriogenology 2005; 63(5): 1290-7. doi: 10.1016/j.theriogenology.2004.06.013 PMID: 15725437
  37. Annandale CH, Holm DE, Ebersohn K, Venter EH. Seminal transmission of lumpy skin disease virus in heifers. Transbound Emerg Dis 2014; 61(5): 443-8. doi: 10.1111/tbed.12045 PMID: 23289592
  38. Salib FA, Osman AH. Incidence of lumpy skin disease among Egyptian cattle in Giza Governorate, Egypt. Vet World 2011; 4(4)
  39. Beard PM. Lumpy skin disease: A direct threat to Europe. Vet Rec 2016; 178(22): 557-8. doi: 10.1136/vr.i2800 PMID: 27235496
  40. Brenner J, Bellaiche M, Gross E, et al. Appearance of skin lesions in cattle populations vaccinated against lumpy skin disease: Statutory challenge. Vaccine 2009; 27(10): 1500-3. doi: 10.1016/j.vaccine.2009.01.020 PMID: 19186204
  41. Sameea Yousefi P, Mardani K, Dalir-Naghadeh B, Jalilzadeh-Amin G. Epidemiological study of lumpy skin disease outbreaks in North-western Iran. Transbound Emerg Dis 2017; 64(6): 1782-9. doi: 10.1111/tbed.12565 PMID: 27633121
  42. Alemayehu G, Zewde G, Admassu B. Risk assessments of lumpy skin diseases in Borena bull market chain and its implication for livelihoods and international trade. Trop Anim Health Prod 2013; 45(5): 1153-9. doi: 10.1007/s11250-012-0340-9 PMID: 23274626
  43. Das M, Chowdhury MS, Akter S, et al. An updated review on lumpy skin disease: Perspective of Southeast Asian countries. J Adv Biotechnol Exp Ther 2021; 4(3): 322-3.
  44. Peck D, Bruce M. The economic efficiency and equity of government policies on brucellosis: Comparative insights from Albania and the United States of America. Rev Sci Tech 2017; 36(1): 291-302. doi: 10.20506/rst.36.1.2629 PMID: 28926008
  45. Molla W, de Jong MCM, Gari G, Frankena K. Economic impact of lumpy skin disease and cost effectiveness of vaccination for the control of outbreaks in Ethiopia. Prev Vet Med 2017; 147: 100-7. doi: 10.1016/j.prevetmed.2017.09.003 PMID: 29254706
  46. Gari G, Grosbois V, Waret-Szkuta A, Babiuk S, Jacquiet P, Roger F. Lumpy skin disease in Ethiopia: Seroprevalence study across different agro-climate zones. Acta Trop 2012; 123(2): 101-6. doi: 10.1016/j.actatropica.2012.04.009 PMID: 22569562
  47. Alexander S, Olga B, Svetlana K, et al. A real-time PCR screening assay for the universal detection of lumpy skin disease virus DNA. BMC Res Notes 2019; 12(1): 371. doi: 10.1186/s13104-019-4412-z PMID: 31262345
  48. Bedeković T, Šimić I, Krešić N, Lojkić I. Detection of lumpy skin disease virus in skin lesions, blood, nasal swabs and milk following preventive vaccination. Transbound Emerg Dis 2018; 65(2): 491-6. doi: 10.1111/tbed.12730 PMID: 29086485
  49. Abdulqa HY, Rahman HS, Dyary HO, Othman HH. Lumpy skin disease. Reproductive Immunol Open Acc 2016; 1: 25. doi: 10.21767/2476-1974.100025
  50. Sudhakar SB, Mishra N, Kalaiyarasu S, et al. Lumpy skin disease (LSD) outbreaks in cattle in Odisha state, India in August 2019: Epidemiological features and molecular studies. Transbound Emerg Dis 2020; 67(6): 2408-22. doi: 10.1111/tbed.13579 PMID: 32304275
  51. EL-Khabaz KH. Rapid laboratory diagnosis of lumpy skin disease by using PCR technique. Magallat Asyut al-Tibiyyat al-Baytariyyat 2014; 60(143): 37-41. doi: 10.21608/avmj.2014.171046
  52. Hasib FMY, Islam MS, Das T, et al. Lumpy skin disease outbreak in cattle population of Chattogram, Bangladesh. Vet Med Sci 2021; 7(5): 1616-24. doi: 10.1002/vms3.524 PMID: 33993641
  53. Möller J, Moritz T, Schlottau K, et al. Experimental lumpy skin disease virus infection of cattle: comparison of a field strain and a vaccine strain. Arch Virol 2019; 164(12): 2931-41. doi: 10.1007/s00705-019-04411-w PMID: 31538254
  54. Jameel GH. Determination of complications decrease the risk factor in Cattle infected by lumpy skin disease virus in diyala province, Iraq. IJMGMR 2016; 2: 1-9.
  55. Requirements for the Production and Quality Control of Vaccines (NB: Version). In: Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Paris, France: World Organisation for Animal Health (OIE) 2018.
  56. Lumpy skin disease. Manual of Diagnostic Tests and Vaccines for Terrestrial Animals. Paris, France: World Organisation for Animal Health 2021; 3.
  57. Kitching RP. Vaccines for lumpy skin disease, sheep pox and goat pox. Dev Biol 2003; 114: 161-7. PMID: 14677686
  58. Tuppurainen ESM, Venter EH, Coetzer JAW, Bell-Sakyi L. Lumpy skin disease: Attempted propagation in tick cell lines and presence of viral DNA in field ticks collected from naturally-infected cattle. Ticks Tick Borne Dis 2015; 6(2): 134-40. doi: 10.1016/j.ttbdis.2014.11.002 PMID: 25468765
  59. Wallace DB, Viljoen GJ. Immune responses to recombinants of the South African vaccine strain of lumpy skin disease virus generated by using thymidine kinase gene insertion. Vaccine 2005; 23(23): 3061-7. doi: 10.1016/j.vaccine.2004.10.006 PMID: 15811653
  60. Katsoulos PD, Chaintoutis SC, Dovas CI, et al. Investigation on the incidence of adverse reactions, viraemia and haematological changes following field immunization of cattle using a live attenuated vaccine against lumpy skin disease. Transbound Emerg Dis 2018; 65(1): 174-85. doi: 10.1111/tbed.12646 PMID: 28391652
  61. Calistri P, De Clercq K, Gubbins S, et al. Lumpy skin disease epidemiological report IV: Data collection and analysis. EFSA J 2020; 18(2): e06010. PMID: 32874220
  62. Haegeman A, De Leeuw I, Mostin L, et al. Comparative evaluation of lumpy skin disease virus-based live attenuated vaccines. Vaccines 2021; 9(5): 473. doi: 10.3390/vaccines9050473 PMID: 34066658
  63. Ayelet G, Abate Y, Sisay T, et al. Lumpy skin disease: Preliminary vaccine efficacy assessment and overview on outbreak impact in dairy cattle at Debre Zeit, central Ethiopia. Antiviral Res 2013; 98(2): 261-5. doi: 10.1016/j.antiviral.2013.02.008 PMID: 23428671
  64. Yeruham I, Nir O, Braverman Y, et al. Spread of lumpy skin disease in Israeli dairy herds. Vet Rec 1995; 137(4): 91-3. doi: 10.1136/vr.137.4.91 PMID: 8533249
  65. Sprygin A, Pestova Y, Bjadovskaya O, et al. Evidence of recombination of vaccine strains of lumpy skin disease virus with field strains, causing disease. PLoS One 2020; 15(5): e0232584. doi: 10.1371/journal.pone.0232584 PMID: 32401805
  66. Davies FG, Otema C. The antibody response in sheep infected with a Kenyan sheep and goat pox virus. J Comp Pathol 1978; 88(2): 205-10. doi: 10.1016/0021-9975(78)90024-5 PMID: 207747
  67. Davies FG. Characteristics of a virus causing a pox disease in sheep and goats in Kenya, with observations on the epidemiology and control. J Hyg 1976; 76(2): 163-71. doi: 10.1017/S0022172400055066 PMID: 177699
  68. Tuppurainen E, Dietze K, Wolff J, et al. Vaccines and vaccination against lumpy skin disease. Vaccines 2021; 9(10): 1136. doi: 10.3390/vaccines9101136 PMID: 34696244
  69. Tuppurainen ESM, Pearson CR, Bachanek-Bankowska K, et al. Characterization of sheep pox virus vaccine for cattle against lumpy skin disease virus. Antiviral Res 2014; 109: 1-6. doi: 10.1016/j.antiviral.2014.06.009 PMID: 24973760
  70. Gari G, Abie G, Gizaw D, et al. Evaluation of the safety, immunogenicity and efficacy of three capripoxvirus vaccine strains against lumpy skin disease virus. Vaccine 2015; 33(28): 3256-61. doi: 10.1016/j.vaccine.2015.01.035 PMID: 26056063
  71. Varshovi HR, Norian R, Azadmehr A, Ahangaran NA. Immune response characteristics of Capri pox virus vaccines following emergency vaccination of cattle against lumpy skin disease virus. Iran J Vet Sci Technol 2017; 9(2): 33-40.
  72. Kumar A, Venkatesan G, Hosamani M, et al. The complete genome sequence of Indian sheeppox vaccine virus and comparative analysis with other capripoxviruses. Gene 2022; 810: 146085. doi: 10.1016/j.gene.2021.146085 PMID: 34843879
  73. Roche X, Rozstalnyy A. Introduction and spread of lumpy skin disease in South, East and Southeast Asia: Qualitative risk assessment and management.In: FAO animal production and health, Paper. Rome: FAO 2021.
  74. Kayesh MEH, Hussan MT, Hashem MA, Eliyas M, Anower AKMM. Lumpy skin disease virus infection: An emerging threat to cattle health in Bangladesh. H&V 2020; 7(4): 97. doi: 10.17582/journal.hv/2020/7.4.97.108
  75. Abdallah FM, El Damaty HM, Kotb GF. Sporadic cases of lumpy skin disease among cattle in Sharkia province, Egypt: Genetic characterization of lumpy skin disease virus isolates and pathological findings. Vet World 2018; 11(8): 1150-8. doi: 10.14202/vetworld.2018.1150-1158 PMID: 30250377
  76. Ben-Gera J, Klement E, Khinich E, Stram Y, Shpigel NY. Comparison of the efficacy of Neethling lumpy skin disease virus and x10RM65 sheep-pox live attenuated vaccines for the prevention of lumpy skin disease – The results of a randomized controlled field study. Vaccine 2015; 33(38): 4837-42. doi: 10.1016/j.vaccine.2015.07.071 PMID: 26238726
  77. Kasem S, Saleh M, Qasim I, et al. Outbreak investigation and molecular diagnosis of Lumpy skin disease among livestock in Saudi Arabia 2016. Transbound Emerg Dis 2018; 65(2): e494-500. doi: 10.1111/tbed.12769 PMID: 29150916
  78. Mathan Kum S. An outbreak of lumpy skin disease in a Holstein Dairy Herd in Oman: A clinical report. Asian J Anim Vet Adv 2011; 6(8): 851-9. doi: 10.3923/ajava.2011.851.859
  79. Khalafalla AI, Gaffar Elamin MA, Abbas Z. Lumpy skin disease: Observations on the recent outbreaks of the disease in the Sudan. Rev Élev Méd Vét Pays Trop 1993; 46(4): 548-50. doi: 10.19182/remvt.9408 PMID: 8073169
  80. Rozstalnyy A, Aguanno R, Beltran-Alcrudo D. Lumpy skin disease: Country situation and capacity reports. EMPRES-Anim. Health 2017; 360: 47.
  81. Abutarbush SM, Tuppurainen ESM. Serological and clinical evaluation of the Yugoslavian RM65 sheep pox strain vaccine use in cattle against lumpy skin disease. Transbound Emerg Dis 2018; 65(6): 1657-63. doi: 10.1111/tbed.12923 PMID: 29873893
  82. Ghorani M, Esmaeili H. Comparison of susceptibility of different goat breeds to live attenuated goatpox vaccine. Small Rumin Res 2022; 212: 106721. doi: 10.1016/j.smallrumres.2022.106721
  83. Hamdi J, Boumart Z, Daouam S, et al. Development and evaluation of an inactivated lumpy skin disease vaccine for cattle. Vet Microbiol 2020; 245: 108689. doi: 10.1016/j.vetmic.2020.108689 PMID: 32456824
  84. Nash AA, Dalziel RG, Fitzgerald JR. Mims’ pathogenesis of infectious disease. Academic Press 2015.
  85. Kitching P. Progress towards sheep and goat pox vaccines. Vaccine 1983; 1(1): 4-9. doi: 10.1016/0264-410X(83)90004-X PMID: 6099642
  86. Kitching RP. The control of sheep and goat pox. Rev Sci Tech 1986; 5(2): 503-11. doi: 10.20506/rst.5.2.241 PMID: 32917076
  87. Guyassa C. Epidemiology and diagnostic methods of lumpy skin disease: A Short Review. Int J Vet Sci Res 2022; 8(2): 064-70.
  88. Tuppurainen ESM, Antoniou S-E, Tsiamadis E, et al. Field observations and experiences gained from the implementation of control measures against lumpy skin disease in South-East Europe between 2015 and 2017. Prev Vet Med 2020; 181: 104600. doi: 10.1016/j.prevetmed.2018.12.006 PMID: 30581092
  89. Morgenstern M, Klement E. The effect of vaccination with live attenuated neethling lumpy skin disease vaccine on milk production and mortality—An analysis of 77 dairy farms in Israel. Vaccines 2020; 8(2): 324. doi: 10.3390/vaccines8020324 PMID: 32575395
  90. Sprygin A, Artyuchova E, Babin Y, et al. Epidemiological characterization of lumpy skin disease outbreaks in Russia in 2016. Transbound Emerg Dis 2018; 65(6): 1514-21. doi: 10.1111/tbed.12889 PMID: 29749049
  91. Sprygin A, Babin Y, Pestova Y, et al. Analysis and insights into recombination signals in lumpy skin disease virus recovered in the field. PLoS One 2018; 13(12): e0207480. doi: 10.1371/journal.pone.0207480 PMID: 30540759
  92. Aleksandr K, Olga B, David WB, et al. Non-vector-borne transmission of lumpy skin disease virus. Sci Rep 2020; 10(1): 7436. doi: 10.1038/s41598-020-64029-w PMID: 32366872
  93. Aspden K, Dijk AA, Bingham J, Cox D, Passmore JA, Williamson AL. Immunogenicity of a recombinant lumpy skin disease virus (neethling vaccine strain) expressing the rabies virus glycoprotein in cattle. Vaccine 2002; 20(21-22): 2693-701. doi: 10.1016/S0264-410X(02)00203-7 PMID: 12034095
  94. Ngichabe CK, Binepal YS, Njiru JW, Carn VM. Evaluation of an immunocapture enzymelinked immunosorbent assay for detection of capripoxviruses. Vet Rec 1999; 145(8): 231-2. doi: 10.1136/vr.145.8.231 PMID: 10499858
  95. Ngichabe CK, Wamwayi HM, Barrett T, Ndungu EK, Black DN, Bostock CJ. Trial of a capripoxvirus-rinderpest recombinant vaccine in African cattle. Epidemiol Infect 1997; 118(1): 63-70. doi: 10.1017/S0950268896007200 PMID: 9042036
  96. Wallace DB, Mather A, Kara PD, et al. Protection of cattle elicited using a bivalent lumpy skin disease virus-vectored recombinant rift valley fever vaccine. Front Vet Sci 2020; 7: 256. doi: 10.3389/fvets.2020.00256 PMID: 32509806
  97. Burgers WA, Ginbot Z, Shen YJ, et al. The novel capripoxvirus vector lumpy skin disease virus efficiently boosts modified vaccinia Ankara human immunodeficiency virus responses in rhesus macaques. J Gen Virol 2014; 95(10): 2267-72. doi: 10.1099/vir.0.067835-0 PMID: 24866849
  98. Shen Y, Douglass NJ, Shephard E, Williamson A. Lumpy skin disease virus, a novel poxvirus vector for candidate HIV-1 vaccines.In: Inaids Research And Human Retroviruses. 140 Huguenot Street, 3rd Fl, New Rochelle, Ny 10801 Usa: Mary Ann Liebert Inc 2008; 24: pp. 137-8.
  99. Abutarbush SM, Ababneh MM, Al Zoubi IG, et al. Lumpy skin disease in jordan: Disease emergence, clinical signs, complications and preliminary-associated economic losses. Transbound Emerg Dis 2015; 62(5): 549-54. doi: 10.1111/tbed.12177 PMID: 24148185
  100. Abutarbush SM. Lumpy skin disease (knopvelsiekte, pseudo-urticaria, neethling virus disease, exanthema nodularis bovis).In: Emerging and re-emerging infectious diseases of livestock. Springer 2017; pp. 309-26.
  101. Gari G, Bonnet P, Roger F, Waret-Szkuta A. Epidemiological aspects and financial impact of lumpy skin disease in Ethiopia. Prev Vet Med 2011; 102(4): 274-83. doi: 10.1016/j.prevetmed.2011.07.003 PMID: 21852008

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