Analysis of the toxicological situation in Moscow in the first three months of the COVID-19 pandemic

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Abstract

Introduction. On March 11, 2020, WHO announced the global COVID-19 pandemic. According to literature data, the spread of coronavirus infection COVID-19 affected the structure of acute chemical poisoning.

The aim. Assessment of the impact of the COVID-19 pandemic and restrictive measures on the peculiarities of seeking advice and the structure of acute chemical poisoning in Moscow. 

Material and methods. The data of the registration forms “Card of recording of a consultation of a patient with acute poisoning of chemical etiology” in the period from March 30 to June 30, 2020 and 2019 were studied. The analysis indicators of a hospitalization of patients in the department of acute poisoning and somatopsychiatric disorders of N.V. Sklifosovsky, the Research Institute of Emergency Medicine.

Results. It was found that in the analyzed period of 2020 compared to 2019, the proportion of injured people of working age decreased by 11.2%, while it increased at the age of 0-17 years by 3.2 times. An increase in the number of consultations for individuals by 2.1 times was noted. There was an increase in the number of complaints about poisoning with antibiotics, drugs from the T45 group (anticoagulants, vitamins, etc.), T37 (antiviral, anti-microbial, etc.) by 1.7-2 times. 

In March-June 2020, there was an increase in the number of complaints about the toxic effects of alcohol (T51), an increase in hospitalized patients with acute alcohol poisoning by 4 times, and with combined alcohol poisoning – by 2.7 times. The number of complaints about poisoning with detergents and disinfectants in the first three months of the pandemic increased by 2.7 times.

Conclusion. The pandemic and the introduction of restrictive measures for COVID-19 have affected the toxicological situation in Moscow, which must be taken into account when determining the guidelines for organizational measures for the provision of medical care for acute chemical poisoning during the COVID-19 pandemic.

About the authors

Anastasiya Yurevna Simonova

Research and Applied Toxicology Center of Federal Medical and Biological Agency; Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Author for correspondence.
Email: simonovatoxy@mail.ru
ORCID iD: 0000-0003-4736-1068

MD, PhD, Leading Researcher, Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department,
Moscow, 107045, Russian Federation.

e-mail: simonovatoxy@mail.ru

Russian Federation

Pavel Gennadevich Rozhkov

Research and Applied Toxicology Center of Federal Medical and Biological Agency

Email: tox65@mail.ru
ORCID iD: 0000-0003-4157-9015

Директор ФГБУ «Научно-практический токсикологический центр» Федерального медико-биологического агентства (ФГБУ НПТЦ ФМБА России), 129090, Москва.

e-mail: tox65@mail.ru 

Russian Federation

Mariya Vladimirovna Belova

Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: maniabel@gmail.ru
ORCID iD: 0000-0002-0861-5945

Доктор биологических наук, ведущий научный сотрудник отделения острых отравлений и соматопсихиатрических расстройств ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ», 107045, Москва.

e-mail: maniabel@gmail.ru 

Russian Federation

Kapitolina Konstsntinovna Ilyashenko

Research and Applied Toxicology Center of Federal Medical and Biological Agency; Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: toxikapa@mail.ru
ORCID iD: 0000-0001-6137-8961

Доктор медицинских наук, профессор, научный консультант отделения острых отравлений и соматопсихиатрических расстройств ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ»,
107045, Москва.

e-mail: toxikapa@mail.ru

Russian Federation

Mikhail Mikhaylovich Potskhveriya

Research and Applied Toxicology Center of Federal Medical and Biological Agency; Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: potskhveriya@mail.ru
ORCID iD: 0000-0003-0117-8663

Кандидат медицинских наук, заведующий отделением острых отравлений и соматопсихиатрических расстройств ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ», 107045, Москва.

e-mail: potskhveriya@mail.ru

Russian Federation

Yuriy Nikolaevich Ostapenko

Research and Applied Toxicology Center of Federal Medical and Biological Agency; Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: ostapenkoyu@mail.ru
ORCID iD: 0000-0002-5023-7685

Кандидат медицинских наук, ведущий научный сотрудник отделения острых отравлений и соматопсихиатрических расстройств ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ», 107045, Москва; руководитель отдела развития федерального банка данных по острой химической патологии ФГБУ «Научно-практический токсикологический центр» Федерального медико-биологического агентства (ФГБУ НПТЦ ФМБА России), 129090, Москва.

e-mail: ostapenkoyu@mail.ru

Russian Federation

Yuriy Semenovich Goldfarb

Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: goldfarb@mail.ru
ORCID iD: 0000-0002-0485-2353

Доктор медицинских наук, профессор, заведующий отделом внешних научных связей ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ», 107045, Москва; заведующий кафедрой клинической токсикологии ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» МЗ РФ, 125993, г. Москва.

e-mail: goldfarb@mail.ru

Russian Federation

Anna Ivanovna Fetisova

Research and Applied Toxicology Center of Federal Medical and Biological Agency

Email: grig3636@gmail.com
ORCID iD: 0000-0002-9225-6382

Кандидат фармацевтических наук, заместитель директора по научной работе ФГБУ «Научно-практический токсикологический центр» Федерального медико-биологического агентства (ФГБУ НПТЦ ФМБА России), 129090, Москва.

e-mail: grig3636@gmail.com

Russian Federation

Alexandr Nikanorovich Elkov

Research and Applied Toxicology Center of Federal Medical and Biological Agency; Department of Acute Poisonings and Somatopsychiatric Disorders, N.V. Sklifosovsky Research Institute for Emergency Medicine, Moscow Health Department

Email: 2bobika@mail.ru
ORCID iD: 0000-0002-5945-503X

Кандидат физико-математических наук, старший научный сотрудник отделения острых отравлений и соматопсихиатрических расстройств ГБУЗ г. Москвы «НИИ СП им. Н.В. Склифосовского ДЗМ», 107045, Москва.

e-mail: 2bobika@mail.ru

Russian Federation

Tatyana Anatolevna Sokolova

Research and Applied Toxicology Center of Federal Medical and Biological Agency

Email: tanyaasokolova@mail.ru
ORCID iD: 0000-0003-2117-4563

Научный сотрудник отдела организации консультативной помощи ФГБУ «Научно-практический токсикологический центр» Федерального медико-биологического агентства (ФГБУ НПТЦ ФМБА России), 129090, Москва.

e-mail: tanyaasokolova@mail.ru

Russian Federation

References

  1. Ostrovskiy D.I., Ivanova T.I. Influence of the new coronovirus COVID-19 infection on human mental health (literature review). Omskiy psikhiatricheskiy zhurnal. 2020; (2-S1): 4-10. https://doi.org/10.24411/2412-8805-2020-10201 (In Russian)
  2. Ofitsial’nyy sayt Mera Moskvy. Dokumenty. Available at: https://www.mos.ru/city/projects/covid-19/documents/ [Accessed: January 25, 2021]. (In Russian)
  3. Lubenitskaya A.N., Ivanova T.I. The world will never become the same – pandemic of the new millennium (review of literature). Omskiy psikhiatricheskiy zhurnal. 2020; (2-S1): 16-22. https://doi.org/10.24411/2412-8805-2020-10203 (In Russian)
  4. Chang A., Schnall A.H., Law R., Bronstein A.C., Marraffa J.M., Spiller H.A., et al. Cleaning and Disinfectant Chemical Exposures and Temporal Associations with COVID-19 – National Poison Data System, United States, January 1, 2020–March 31, 2020. MMWR Morb Mortal Wkly Rep. 2020; 69(16): 496-8. https://doi.org/10.15585/mmwr.mm6916e1
  5. Sefidbakht S., Lotfi M., Jalli R., Moghadami M., Sabetian G., Iranpour P. Methanol toxicity outbreak: when fear of COVID-19 goes viral. Emerg Med J. 2020; 37(7): 416. https://doi.org/10.1136/emermed-2020-209886
  6. Pollard M.S., Tucker J.S., Green H.D. Jr. Changes in Adult Alcohol Use and Consequences During the COVID-19 Pandemic in the US. JAMA Netw Open. 2020; 3(9): e2022942. https://doi.org/10.1001/jamanetworkopen.2020.22942)
  7. Belova M.V., Il’yashenko K.K., Simonova A.Yu., et al. Struktura ostryh ekzotoksikozov v pervye tri mesyaca pandemii COVID-19 (po dannym otdeleniya ostryh otravlenij GBUZ «NII skoroj pomoshchi im. N.V. Sklifosovskogo DZM»). Neotlozhnaya medicinskaya pomoshch’. 2021; 10(1): 27-32. (In Russian)
  8. Luzhnikov E.A. Medical toxicology: National guidelines [Meditsinskaya toksikologiya: natsional’noe rukovodstvo]. Moscow: GEOTAR-Media; 2012. (In Russian)
  9. Khoffman R., Nel’son L., Khauland M.E., L’yuin N., Flomenbaum N., Goldfrank L. Emergency medical care for poisoning: translated from English [Ekstrennaya meditsinskaya pomoshch’ pri otravleniyakh: per. s angl.] Moscow: Praktika; 2010. (In Russian)
  10. Baeza S., Watkins S.A., Borron S. COVID-19 Crisis Collaboration: The poison Center and Health Department in time of Pandemic. Clin Toxicol. 2020; 58(11: Abstracts North American Congress of Clinical Toxicology (NACCT) - 2020). Abstr #30.
  11. Beuhler M., Beuhler P., Dulaney A., Steverson A., Taylor R., Rembert R. The Inception, Execution and Sunsetting of a Poison Center based COVID-19 Information Line. Clin Toxicol. 2020; 58(11: Abstracts North American Congress of Clinical Toxicology (NACCT) - 2020). Abstr #35.
  12. Calello D., Ruck B., Meaden C., Nelson L. The Poison Center as Pandemic Response: Establishment and Characteristics of a COVID-19 Hotline through the New Jersey Poison Cent. Clin Toxicol. 2020; 58(11): Abstracts North American Congress of Clinical Toxicology (NACCT) - 2020). Abstr #52.
  13. Chen R., Roper L., Krueger J. Trend of toxic alcohol ingestions in the setting of the COVID-19 global pandemic. Clin Toxicol. 2020; 58(11: Abstracts North American Congress of Clinical Toxicology (NACCT) - 2020). Abstr #58.
  14. Ferruzzi M., Celentano A., Sesano F., Milanesi G., Assisi F., Bissoli M., et al. Desinfectant and hand sanitizer product exposures in Italy: a «side effect» of the COVID-19 Pandemic. Clin Toxicol. 2020; 58(11: Abstracts North American Congress of Clinical Toxicology (NACCT) - 2020). Abstr #57.
  15. Cohle S.D., Thompson W., Eisenga B.H., Cottingham S.L. Unexpected death due to chloramine toxicity in a woman with a brain tumor. Forensic Sci Int. 2001; 124(2–3): 137–9. https://doi.org/10.1016/s0379-0738(01)00592-8
  16. Bracco D., Dubois M.J., Bouali R. Intoxication by bleach ingestion. Can J Anaesth. 2005; 52(1): 118–9. https://doi.org/10.1007/BF03018599
  17. National Research Council. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 4. Washington (DC): National Academies Press; 2004. https://doi.org/10.17226/10902
  18. Medina-Ramón M., Zock J.P., Kogevinas M., Sunyer J., Torralba Y., Borrell A., et al. Asthma, chronic bronchitis, and exposure to irritant agents in occupational domestic cleaning: a nested case-control study. Occup Environ Med. 2005; 62(9): 598–606. https://doi.org/10.1136/oem.2004.017640
  19. Babić Ž., Turk R., Macan J. Toxicological aspects of increased use of surface and hand disinfectants in Croatia during the COVID-19 pandemic: a preliminary report. Arh Hig Rada Toksikol. 2020; 71(3): 261-4. https://doi.org/10.2478/aiht-2020-71-3470

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Copyright (c) 2021 Simonova A.Y., Rozhkov P.G., Belova M.V., Ilyashenko K.K., Potskhveriya M.M., Ostapenko Y.N., Goldfarb Y.S., Fetisova A.I., Elkov A.N., Sokolova T.A.



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