NEPHROPROTECTIVE ACTION OF COMBINATION OF TAURINE WITH ZINC DIASPARTATE IN RATS WITH GENTAMICIN NEPHROPATHY
- Authors: Basalai O.N.1, Mikhalchuk E.C.1, Zimatkin S.M.1, Bushma M.I.1, Borisenok O.A.1
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Affiliations:
- Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
- Issue: No 5 (2015)
- Pages: 21-24
- Section: Articles
- Published: 01.10.2015
- URL: https://rjsocmed.com/0869-7922/article/view/641338
- DOI: https://doi.org/10.15690/vramn510
- ID: 641338
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Abstract
In rats with gentamicin nephropathy (gentamicin injected intra-abdominally, 60 mg/kg daily over 10 days), a combination of taurine with zinc diaspartate administrated in the stomach in the ratio of 1.0 g + 0.14g -250 mg/kg and particularly of 1.0+0.06 g - 500 mg/ kg ) has a nephroprotective effect that is proved by weakened lesions of cortical nephrons proximal convoluted tubules.
About the authors
Olga Nikolaevna Basalai
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Author for correspondence.
Email: noemail@neicon.ru
Аспирант кафедры фармакологии им. проф. М.В. Кораблева УО ГрГМУ, 230023, г. Гродно, Беларусь
e-mail: basalai2012@mail.ru
Russian FederationElena Cheslavovna Mikhalchuk
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Email: noemail@neicon.ru
К.б.н., доцент каф. гистологии, цитологии и эмбриологии УО ГрГМУ, 230023, г. Гродно, Беларусь
e-mail: milena6519@mail.ru
Russian FederationSergey Mikhaylovich Zimatkin
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Email: noemail@neicon.ru
Д.б.н., профессор, зав. каф. гистологии, цитологии и эмбриологии УО ГрГМУ, 230023, г. Гродно, Беларусь
e-mail: zimatkin@grsmu.by
Russian FederationMikhail Ivanovich Bushma
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Email: noemail@neicon.ru
Д.м.н., профессор кафедры фармакологии им. профессора М.В. Кораблева УО ГрГМУ, 230023, г. Гродно, Беларусь
e-mail: pharma@grsmu.by
Russian FederationOlga Aleksandrovna Borisenok
Education establishment «Grodno State Medical University» of Ministry of health of Republic of Belarus: M.V. Korablev
Email: noemail@neicon.ru
К.м.н., ст. преподаватель кафедры фармакологии им. профессора М.В. Кораблева УО ГрГМУ, 230023, г. Гродно, Беларусь
pharma@grsmu.by
Russian FederationReferences
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