SOME PRINCIPLES AND MEANS OF INCREASING THE ORGANISM’S RESISTANCE TO ADVERSE EFFECTS OF METALCONTAINING NANOPARTICLES

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Abstract

Particularly high health risks associated with impacts of metal and metal oxide nanoparticles (Me-NPs), and their presence in the occupational environment, not only in nano-industry, but also in some long-existing technologies as well necessitates to maintain levels of hazardous exposures as low as possible and also to find ways to enhance the body’s resistance to them. The article briefly discusses the theoretical background of suсh a «bio-protection». The analysis of the most significant results of experiments with different Me-NPs, shows that against the background of properly selected combinations of certain biologically active agents used in harmless doses, it can be possible to significantly weaken integral and specific toxicity and even genotoxicity of metal-containing nanoparticles.

About the authors

L. I. Privalova

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Author for correspondence.
Email: noemail@neicon.ru
Russian Federation

B. A. Katsnelson

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

V. B. Gurvich

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

I. A. Minigalieva

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

M. P. Sutunkova

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

O. H. Makeyev

Central Research Laboratory, Ural State Medical University

Email: noemail@neicon.ru
Russian Federation

I. E. Valamina

Central Research Laboratory, Ural State Medical University

Email: noemail@neicon.ru
Russian Federation

V. Y. Shur

Ural Center for Shared Use «Modern Nanothechnologies»,Ural Federal University named after B.N. Eltsin, the first President of Russia

Email: noemail@neicon.ru
Russian Federation

E. V. Grigoryeva

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

S. V. Klinova

Ekaterinburg Medical Research Center for Prophylaxis and Health Protection in Industrial Workers, Rospotrebnadzor

Email: noemail@neicon.ru
Russian Federation

E. V. Shishkina

Ural Center for Shared Use «Modern Nanothechnologies»,Ural Federal University named after B.N. Eltsin, the first President of Russia

Email: noemail@neicon.ru
Russian Federation

References

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Copyright (c) 2016 Privalova L.I., Katsnelson B.A., Gurvich V.B., Minigalieva I.A., Sutunkova M.P., Makeyev O.H., Valamina I.E., Shur V.Y., Grigoryeva E.V., Klinova S.V., Shishkina E.V.


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