Age trend in the mortality from diseases of the circulatory system during the pandemic under a decrease in air pollution
- Authors: Efimova N.V.1, Bobkova E.V.1,2, Zarodnyuk T.S.3, Gornov A.Y.3
-
Affiliations:
- East Siberian Institute of Medical and Ecological Research
- Medical Information and Analytical Center of the Irkutsk Region
- Institute of System Dynamics and Control Theory named after V.M. Matrosov, SB RAS
- Issue: Vol 103, No 9 (2024)
- Pages: 925-931
- Section: ENVIRONMENTAL HYGIENE
- Published: 15.12.2024
- URL: https://rjsocmed.com/0016-9900/article/view/646056
- DOI: https://doi.org/10.47470/0016-9900-2024-103-9-925-931
- EDN: https://elibrary.ru/lgcdfm
- ID: 646056
Cite item
Abstract
Introduction. The results of large-scale studies of the mortality from diseases of the circulatory system (DCS) during the pandemic require further analysis of the data and the search for modifying factors.
The purpose is to identify the features of the trend in the mortality from DCS in the population of an industrial center during a pandemic under changes in air pollution.
Materials and methods. The research was carried out in the industrial center — Bratsk. Age-specific mortality rates were studied using exponential models in the background (2017) and pandemic (2021) periods. The contribution of atmospheric air pollution to the mortality rate was calculated in accordance with the “Guidelines for assessing the risk to public health from exposure to chemical substances that pollute the environment.”
Results. The age-related increase in the mortality rate from DCS over 2017 was 125%, and during 2021 – 172%. During the pandemic, the excess mortality rate was in cases older 80 years — 35.92‰, 70–79 — 8.48‰, 60–69 — 1.03‰. PM10 levels in the air decreased from high to alarming levels in 2021, resulting in a reduction in excess PM10-related deaths from 194 (CI: 193.6–195.1) to 5.0 (CI: 4.8–5.1) cases.
Limitations are associated with incomplete epidemiological knowledge about the dependence of mortality from DCS on exposure to air pollutants.
Conclusion. The use of nonlinear regression analysis made it possible to demonstrate changes in trends in age-specific mortality during the background period and during the pandemic. During the pandemic, the level of excess mortality was revealed to relate with PM10 air pollution decreased.
Compliance with ethical standards. The study does not require submission of the opinion of the biomedical ethics committee or other documents.
Contributions:
Efimova N.V. — the concept and design of the study, writing the text, editing;
Bobkova E.V. — collection of material and data processing, writing the text;
Zarodnyuk T.S. — data processing and math modelling, writing the text;
Gornov A.Yu. — the concept of the study, editing.
All authors are responsible for the integrity of all parts of the manuscript and approval of the manuscript final version.
Conflict of interest. The authors declare the absence of obvious and potential conflicts of interest in connection with the publication of this article.
Acknowledgement. The study was carried out within the framework of the state assignment of East-Siberian Institute of Medical and Ecological Research.
Received: May 20, 2024 / Accepted: June 19, 2024 / Published: October 16, 202
Keywords
About the authors
Natalya V. Efimova
East Siberian Institute of Medical and Ecological Research
Email: medecolab@inbox.ru
MD, DSc, professor, leading researcher of the Laboratory of Environmental and Hygienic Research of the East Siberian Institute of Medical and Ecological Research, Angarsk, 665827, Russian Federation
e-mail: medecolab@inbox.ru
Elena V. Bobkova
East Siberian Institute of Medical and Ecological Research; Medical Information and Analytical Center of the Irkutsk Region
Email: evb@miac-io.ru
MD, Deputy Director for Medical Statistics, Medical Information and Analytical Center of the Irkutsk Region, Irkutsk, 664003, Russian Federation
e-mail: evb@miac-io.ru
Tatyana S. Zarodnyuk
Institute of System Dynamics and Control Theory named after V.M. Matrosov, SB RAS
Email: tz@icc.ru
PhD, senior researcher at the Laboratory of Optimal Control of the Institute of System Dynamics and Control Theory named after. V.M. Matrosov, SB RAS, Irkutsk, 664033, Russian Federation
e-mail: tz@icc.ru
Alexander Yu. Gornov
Institute of System Dynamics and Control Theory named after V.M. Matrosov, SB RAS
Author for correspondence.
Email: gornov@icc.ru
DSc (tech), chief researcher of the Laboratory of Optimal Control of the Institute of System Dynamics and Control Theory named after V.M. Matrosov, SB RAS, Irkutsk, 664033, Russian Federation
e-mail: gornov@icc.ru
References
- Zaitseva N.V., Kir’yanov D.A., Kamaltdinov M.R., Ustinova O.Yu., Babina S.V., Tsinker M.Yu., et al. Health risks analysis and complex procedure for estimating the efficiency of targeted activities performed within regional public healthcare systems and aimed at reducing mortality among the population caused by cardiovascular diseases and oncologic diseases. Zdravookhranenie Rossiiskoi Federatsii. 2021; 65(4): 302–9. https://doi.org/10.47470/0044-197X-2021-65-4-302-309 https://elibrary.ru/dvuudg (in Russian)
- GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021; 20(10): 795–820. https://doi.org/10.1016/s1474-4422(21)00252-0
- Usacheva E.V., Nelidova A.V., Kulikova O.M., Flyanku I.P. Mortality of Russian able-bodied population from cardiovascular diseases. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2021; 100(2): 159–65. https://doi.org/10.47470/0016-9900-2021-100-2-159-165 https://elibrary.ru/ildcnn (in Russian)
- Yakovleva T.P., Mikhailova N.S., Tikhonova G.I., Kalitina M.A. The comparative analysis of incidence and mortality of the population living in various climatic zones of Russia. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2018; 97(9): 813–8. https://doi.org/10.47470/0016-9900-2018-97-9-813-818 https://elibrary.ru/ymkawd (in Russian)
- Zubko A.V., Sabgaida T.P., Semenova V.G., Muzykantova N.N. Mortality associated with preventable causes of deaths from cardio-vascular diseases in the pre-COVID period and during the pandemic in Russia. Sotsial’nye aspekty zdorov’ya naseleniya. 2023; 69(1): 6. https://doi.org/10.21045/2071-5021-2023-69-1-6 https://elibrary.ru/igkrts (in Russian)
- Kobyakova O.S., Starodubov V.I., Khalturina D.A., Zykov V.A., Zubkova T.S., Zamyatnina E.S. Promising measures to reduce the mortality rate in Russia: an analytical review. Zdravookhranenie Rossiiskoi Federatsii. 2021; 65(6): 573–80. https://doi.org/10.47470/0044-197X-2021-65-6-573-580 https://elibrary.ru/tvvabt (in Russian)
- Sedykh D.Yu., Barbarash O.L., Indukaeva E.V., Artamonova G.V. Selected public health indicators in the Siberian Federal District, the impact of COVID-19. Sotsial’nye aspekty zdorov’ya naseleniya. 2023; 69(5): 3. https://doi.org/10.21045/2071-5021-2023-69-5-3 (in Russian)
- Ungvari Z., Tarantini S., Donato A.J., Galvan V., Csiszar A. Mechanisms of vascular aging. Circ. Res. 2018; 123(7): 849–67. https://doi.org/10.1161/circresaha.118.311378
- Liu C., Cai J., Chen R., Sera F., Guo Y., Tong S., et al. Coarse particulate air pollution and daily mortality: a global study in 205 cities. Am. J. Respir. Crit. Care Med. 2022; 206(8): 999–1007. https://doi.org/10.1164/rccm.202111-2657oc
- Health Effects Institute. State of Global Air 2020. Special Report. Boston: Health Effects Institute; 2020. Available by: https://stateofglobalair.org/sites/default/files/documents/2020-10/soga-2020-report.pdf
- Tan T., Hu M., Li M., Guo Q., Wu Y., Fang X., et al. New insight into PM2.5 pollution patterns in Beijing based on one-year measurement of chemical compositions. Sci. Total. Environ. 2018; 621: 734–43. https://doi.org/10.1016/j.scitotenv.2017.11.208
- Huang W., Zhou Y., Chen X., Zeng X., Knibbs L.D., Zhang Y., et al. Individual and joint associations of long-term exposure to air pollutants and cardiopulmonary mortality: a 22-year cohort study in Northern China. Lancet Reg. Health West Pac. 2023; 36: 100776. https://doi.org/10.1016/j.lanwpc.2023.100776
- Lee W.E., Park S.W., Weinberger D.M., Olson D., Simonsen L., Grenfell B.T., et al. Direct and indirect mortality impacts of the COVID-19 pandemic in the US, March 2020 – April 2021. medRxiv. 2022. Preprint. https://doi.org/10.1101/2022.02.10.22270721
- Shlyakhto E.V., Konradi A.O., Karonova T.L., Fedotov P.A. COVID-19 Pandemic and cardiovascular diseases: lessons and prospects. Vestnik Rossiiskoi akademii nauk. 2022; 92(7): 686–90. https://doi.org/10.1134/S1019331622040098 https://elibrary.ru/xjbayq (in Russian)
- Kanorskii S.G. COVID-19 and the heart: direct and indirect impact. Kubanskii nauchnyi meditsinskii vestnik. 2021; 28(1): 16–31. https://doi.org/10.25207/1608-6228-2021-28-1-16-31 https://elibrary.ru/wzllgs (in Russian)
- Kouhpayeh H. Clinical features predicting COVID-19 mortality risk. Eur. J. Transl. Myol. 2022; 32(2): 10268. https://doi.org/10.4081/ejtm.2022.10268
- Bunova S.S., Okhotnikova P.I., Skirdenko Yu.P., Nikolaev N.A., Osipova O.A., Zhernakova N.I. COVID-19 and cardiovascular comorbidity: novel approaches to reduce mortality. Kardiovaskulyarnaya terapiya i profilaktika. 2021; 20(4): 2953. https://doi.org/10.15829/1728-8800-2021-2953 https://elibrary.ru/wopwrt (in Russian)
- Chang J., Deng Q., Guo M., Ezzati M., Baumgartner J., Bixby H., et al. Trends and inequalities in the incidence of acute myocardial infarction among Beijing townships, 2007–2018. Int. J. Environ. Res. Public Health. 2021; 18(23): 12276. https://doi.org/10.3390/ijerph182312276
- Barbarash O.L., Boitsov S.A., Vaisman D.Sh., Galyavich A.S., Drapkina O.M., Zabozlaev F.G., et al. Position statement on challenges in assessing cause-specific mortality. Kompleksnye problemy serdechno-sosudistykh zabolevanii. 2018; 7(2): 6–9. https://doi.org/10.17802/2306-1278-2018-7-2-6-9 https://elibrary.ru/xturqd (in Russian)
- Efimova N.V., Rukavishnikov V.S. Assessment of air pollution based on the analysis of long-term observations in the city of Bratsk. Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2022; 101(9): 998–1003. https://doi.org/10.47470/0016-9900-2022-101-9-998-1003 https://elibrary.ru/aaoibc (in Russian)
- Aslamova V.S., Plekhanova O.S., Aslamov A.A. Regression models for assessing atmospheric pollutant emissions in the cities of Bratsk and Cheremkhovo. Matematicheskie metody v tekhnologiyakh i tekhnike. 2023; (11): 79–82. https://doi.org/10.52348/2712-8873_MMTT_2023_11_79 https://elibrary.ru/fghrfv (in Russian)
- Mai I.V., Klein S.V., Maksimova E.V. Effectiveness of the activities of the federal project «Clean air» by the quality of atmospheric air and risk for the health (by means of the example of the city Bratsk). Gigiena i Sanitaria (Hygiene and Sanitation, Russian journal). 2023; 102(12): 1367–74. https://doi.org/10.47470/0016-9900-2023-102-12-1367-1374 https://elibrary.ru/zkowwh (in Russian)
- Gornov A.Yu., Zarodnyuk T.S., Anikin A.S., Sorokovikov P.S., Tyatyushkin A.I. Software engineering for optimal control problems. Lecture Notes in Networks and Systems. 2022; 424: 415–26. https://doi.org/10.1007/978-3-030-97020-8_38
- Dontsov V.I. Changes in mortality, life expectancy and the rate of aging in the XX century: possible causes. Zdravookhranenie Rossiiskoi Federatsii. 2021; 65(1): 17–23. https://doi.org/10.47470/0044-197X-2021-65-1-17-23 https://elibrary.ru/flezau (in Russian)
- Kontsevaya A.V., Shal’nova S.A., Drapkina O.M. ESSE-RF study: epidemiology and public health promotion. Kardiovaskulyarnaya terapiya i profilaktika. 2021; 20(5): 2987. https://doi.org/10.15829/1728-8800-2021-2987-39 https://elibrary.ru/wlwtjw (in Russian)
- Tadayon S., Wickramasinghe K., Townsend N. Examining trends in cardiovascular disease mortality across Europe: how does the introduction of a new European Standard Population affect the description of the relative burden of cardiovascular disease? Popul. Health Metr. 2019; 17(1): 6. https://doi.org/10.1186/s12963-019-0187-7 https://elibrary.ru/fwclff
- Baek J., Lee H., Lee H.H., Heo J.E., Cho S.M.J., Kim H.C. Thirty-six-year trends in mortality from diseases of circulatory system in Korea. Korean Circ. J. 2021; 51(4): 320–32. https://doi.org/10.4070/kcj.2020.0424
- Voevoda M.I., Chernyshev V.M., Mingazov I.F. Features of natural population movement in the Siberian Federal District during the coronavirus pandemic. Sibirskii nauchnyi meditsinskii zhurnal. 2023; 43(5): 184–94. https://doi.org/10.18699/SSMJ20230521 (in Russian)
- Semenova V.G., Ivanova A.E., Sabgaida T.P., Evdokushkina G.N., Zaporozhchenko V.G. The first year of the pandemic: social response in the context of causes of death. Zdravookhranenie Rossiiskoi Federatsii. 2022; 66(2): 93–100. https://doi.org/10.47470/0044-197X-2022-66-2-93-100 https://elibrary.ru/hcevmg (in Russian)
- Lefler J.S., Higbee J.D., Burnett R.T., Ezzati M., Coleman N.C., Mann D.D., et al. Air pollution and mortality in a large, representative U.S. cohort: multiple-pollutant analyses, and spatial and temporal decompositions. Environ. Health. 2019; 18(1): 101. https://doi.org/10.1186/s12940-019-0544-9
Supplementary files
